Detroit, Michigan, sits on the banks of the Detroit River

iss073e0814049 (Sept. 26, 2025) --- Detroit, Michigan, sits on the banks of the Detroit River, which connects Lake St. Clair (center) to Lake Erie to the south. To the north, the St. Clair River links Lake St. Clair with Lake Huron. Both rivers serve as natural borders between the United States and Canada. The International Space Station was orbiting 259 miles above Ontario, Canada, at the time of this photograph.