ADCs in Microgravity (CASIS)

iss052e018944 (7/24/2017) --- NASA astronaut Peggy Whitson working with the Efficacy and Metabolism of Azonafide Antibody-Drug Conjugates in Microgravity (ADCs in Microgravity). The ADCs in Microgravity investigation evaluates new antibody-drug conjugates that combine an immune-activating drug with antibodies in order to target only cancer cells, increasing the effectiveness of chemotherapy and reducing its side effects. In microgravity, cancer cells grow in three-dimensional, spheroid structures that closely resemble their form in the human body, allowing for better drug testing. This investigation may accelerate development of targeted therapies for cancer patients.